Hyun-Joon Ha · Se In Son · Won Koo Lee · Jieun Choi



Diversely substituted oxindoles were obtained from atom economical direct C–C bond formation reactions of various substituted anilides and pyridinylamides with metal salts and oxides. The catalysts include CuO, Cu2O, FeCl3, Fe2O3, TiO2, ZnO, and Ag2O and their nanoparticles. The reaction proceeds under solvent-free and aerobic conditions in excellent yields. The reaction mechanism was proved to be a single electron transfer pathway with oxygen as the re-oxidant of the metal catalysts.



Graphical abstract: Atom economical synthesis of oxindoles by metal-catalyzed intramolecular C–C bond formation under solvent-free and aerobic conditions

List of Articles
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